#200, Lower East Side, NYC
Over the past few years, it's become innundated with improbable high rises and lifeless luxury hotels, but you can still count on the Lower East Side for some good old-fashioned grassroots murals. I've seen plenty of graffiti spray-painted over shop windows protesting the yuppification of the LES, but I'm about style as well as substance, and this wall of misbehaving kitties gets it just right. The full text of the newspaper headline reads: Lower East Side Rejoices as Yuppies Commit Mass Suicide. Not pictured is the syringe by the kitty's side.